NGSengine case studies

In this webinar, we will deal with challenging case studies for in-depth data analysis and interactive discussions.

You will receive data files in advance. We ask you to analyze the data and think about what you would report to the clinician. Before the webinar, we would like to receive your answers and questions on education@gendx.com so we can address them in the live webinar (trial license available on request).
We look forward to receiving your interpretation of the data!

Attend the webinar and receive 0.15 continuing education credits (CECs).

   

Transitioning to NGS: Why, and what to consider?

As HLA typing lab, you might consider moving to NGS as a method for HLA typing. What are the advantages and what are the factors to consider when making such a move. We will discuss instrumentation, ancillary equipment and other less obvious factors to make an informed decision.

Attend the webinar and receive 0.15 continuing education credits (CECs).

KIR

Registration will open soon.

NGSengine case studies

You will receive data files in advance. We ask you to analyze the data and think about what you would report to the clinician. Before the webinar we would like to receive your answers and questions on education@gendx.com so we can address them in the live webinar. (trial license available on request) We look forward to receiving your interpretation of the data!

Attend the webinar and receive 0.15 continuing education credits (CECs).

NGSengine case studies

In the last webinar of the May series we will deal with challenging case studies for in-depth data analysis and interactive discussions.
This webinar, Hanneke Merkens PhD (Associate Director Support & Education, GenDx) and Erik Rozemuller PhD (Senior Scientist Bioinformatics, GenDx) will use samples of two loyal webinar listeners.

You will receive data files in advance. We ask you to analyze the data and think about what you would report to the clinician. Before the webinar we would like to receive your answers and questions on education@gendx.com so we can address them in the live webinar. (trial license available on request) We look forward to receiving your interpretation of the data!

Attend the webinar and receive 0.15 continuing education credits (CECs). Fill out the survey after the webinar to apply.

                 

Daily practice in an HLA lab: dealing with HLA-DR, a complicated genetic region

The DR locus of the class II HLA region is unique. Compared to the other classical class II HLA molecules, HLA-DQ and HLA-DP, each of which has a single, polymorphic locus encoding for the alpha and beta chains, the HLA-DR molecule is comprised of an essentially monomorphic alpha chain, and multiple, polymorphic loci that encode for the beta chain. Additionally, there is variability in the number of loci encoding for the beta chains, with either one or two HLA-DRB loci per chromosome. This genetic complexity can lead to challenges in typing HLA-DR for clinical purposes.

In this webinar Dr. Nicholas Brown will discuss the genetic structure of HLA-DR, and discuss how the complexity can be managed.

Variability in HLA expression: Impact on histocompatibility assay interpretation and immunologic risk assessment

Assessment of immunologic risk in solid organ transplantation is one of the primary functions of an HLA laboratory. The risk assessment is based on the cumulative interpretation of multiple assays used to measure HLA antibodies and the believed understanding of HLA in the allograft. What is not well recognized is the degree of variability in HLA molecules immobilized onto Luminex single antigen beads, variable HLA expression on T and B lymphocytes used in cell-based crossmatches, and biologically encoded differences affecting in vivo HLA expression. Variable HLA expression is therefore inherent across all assays used in HLA laboratories as well as donor HLA targeted by recipient HLA antibodies.

In this webinar, Dr. Hidalgo will provide a brief overview of these concepts and how they impact the interpretation of immunologic risk in transplant recipients. Live chat will be open for your questions or comments

Webinar 4 out of 4: GenDx case studies (advanced level)

In the third webinar of the series we will deal with challenging case studies for in-depth data analysis and interactive discussions.

-Live discussion of NGS data
-Tips and tricks

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

Webinar 3 out of 4: GenDx case studies (easy/medium level)

In the third webinar of the series we will deal with challenging case studies for in-depth data analysis and interactive discussions.

-Live discussion of NGS data
-Tips and tricks

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

Webinar 2 out of 4: Introduction to NGSengine®

In the second webinar of the series, discover the basic principals of the NGS workflow and see how data analysis in NGSengine® works.

-NGSengine® software demo
-Tips and tricks for effective data analysis
-Demonstration of a GenDx case study

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

Webinar 1 out of 4: Basics of NGS workflow

In the first webinar of the series, discover the basic principals of the NGS workflow and see how data analysis in NGSengine® works.

-Introduction about high-resolution HLA typing with NGS
-NGS workflows for HLA typing

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

Multiplex amplification for fast and easy HLA typing

At GenDx we strive for fast and easy sequencing-based HLA typing. Using a multiplexed PCR strategy significantly reduces pipetting steps and hands-on time. In this webinar, Sake van Wageningen PhD, Project Manager R&D, will present the GenDx multiplexed strategies and give a development update on our latest 11-loci multiplex product. He will also demonstrate how multiplexed data is analyzed in NGSengine.

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

How to deal with an incomplete allele

Incomplete HLA genes in the IMGT database can form a challenge in data analysis. In this webinar, Maarten Penning, Chief Technology Officer, will explain how the NGSengine software handles incomplete alleles. Using case studies directly from the field, he will show examples of the benefits and challenges of extrapolated data, and how to interpret your results when no extrapolated data is available.

Topics to be discussed:
• Extrapolated data explained
• NGSengine case studies from the field

Live chat will be open for your questions or comments

NEW! Attend the webinar and receive 0.15 continuing education credits (CECs).

Register to webinar 12.00-12.30 pm CET (Amsterdam, NL) via this link
Register to webinar 12.00-12.30 pm CST (Chicago, IL, USA) via this link