Post-transplant monitoring of the recipient chimeric state is essential for the early detection of relapse after stem cell transplantation. Currently, monitoring is mainly performed through STR or qPCR testing. For STR, its laborious nature and low sensitivity are disadvantages. While qPCR is considerably less effort to perform and results in higher sensitivity, each monitoring experiment requires a recipient pre-transplant sample.

Performing chimerism monitoring by next-generation sequencing (NGS) allows for the sensitive detection of markers, without requiring pre-transplant DNA for each monitoring experiment.

In this webinar, we will present to you NGStrack® and TRKengine®, which will enable you to perform chimerism monitoring by NGS. We will go into the NGStrack® product design, the laboratory workflow and assay performance from analytical and proficiency studies. In addition, a preview is given of TRKengine®, the novel software package in development for the analysis of NGS based chimerism results.

Attend the webinar and receive 0.15 continuing education credits (CECs).