GenDx > GenDx Products > NGS HLA Typing

NGS HLA Typing

NGS-based Human Leukocyte Antigen (HLA) typing provides high-resolution, accurate results essential for stem cell and organ transplantation. By enabling reliable matching of patients and donors, it helps reduce the risk of graft-versus-host disease and improve transplant success. Our NGS HLA typing solutions offer flexibility, scalability, and compatibility with major sequencing platforms.

Single-locus HLA typing for maximum flexibility on ONT

NGSgo®-ProntoFLX

Single locus HLA typing on ONT
  • Whole-gene amplification
  • Compatible with ONT devices
  • Available as RUO
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NGS-Pronto 11 loci HLA Amplification for nanopore and Illumina sequencing

NGSgo®-ProntoAmp

11 loci - Illumina and ONT
  • RUO and CE-marked IVD (IVDR)
  • PCR time 90 minutes
  • 11 HLA loci (3-tube multiplex)
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NGS-ProntoPrep

Library preparation for ONT
  • Barcoded library prep for ONT (RUO)
  • Fast workflow in 1.5–2 hours
  • 1 to 96 samples
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NGS-Turbo prep and TurboAmp kits for 11-loci HLA typing using Oxford nanopore sequencing

NGS-Turbo®

11 loci - ONT
  • Amplification & barcoded library prep
  • DNA to results ~2.5h
  • 1 sample per run
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MX11-3 11 loci multiplex amplification for Illumina, Ion Torrent, PacBio

NGSgo®-MX11-3

11 loci - Illumina, Ion Torrent, PacBio
  • Multiplex amplification
  • Whole-gene coverage
  • RUO & CE-IVD (IVDR)
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NGSgo MX6-1 kit for 6-loci HLA typing in a single tube, compatible with Illumina and PacBio sequencing platforms

NGSgo®-MX6-1

6 loci - Illumina and PacBio
  • One-Day-Workflow
  • 6 loci in 1 tube
  • RUO & CE-IVD (IVDR)
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NGSgo Library Full Kit by GenDx with reagent bottles, color-coded tubes, PCR plate, and packaging for NGS library preparation workflows

NGSgo® Library Full Kit

Library prep and indexing - Illumina
  • Complete solution for library preparation
  • Includes NGSgo-LibrX, NGSgo-IndX plate & GenDx-AMPure XP beads
  • RUO & CE-IVD (IVDR)
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96-well plate with tube

NGSgo®-IndX

Indexing - Illumina and Ion Torrent
  • Fast and easy indexing
  • Well plate format
  • RUO
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Library prep for Illumina and Ion Torrent

NGSgo®-LibrX

Library prep - Illumina and Ion Torrent
  • Fast library preparation
  • Enzymatic fragmentation
  • RUO
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HLA typing Polymerase mastermix

GenDx-LongMix

Polymerase mastermix
  • Ready-to-go enzyme mastermix
  • Buffer and dNTPs already included
  • Compatible with NGSgo
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HLA typing Magnetic SPRI beads for DNA cleanup

GenDx-AMPure XP

Magnetic SPRI beads for DNA cleanup
  • High recovery of amplicons
  • Consistent size selection
  • Compatible with manual and automated processing
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NGSengine®

Analysis software for NGS-based typing
  • Regular updates included
  • Intuitive interface
  • RUO & CE-IVD
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