KMRtrack®

Monitoring kit to track chimeric status in time

Benefits

  • Monitor selected markers
  • Early relapse detection
  • Complete kit or single markers

Description

High-sensitivity donor-recipient chimerism monitoring can aid in the diagnosis of leukemia relapse and facilitate timely clinical intervention. Our KMRtype kits can be used to determine presence or absence of genetic markers for chimerism monitoring. By using the qPCR technique, a sensitivity of as low as 0.05% can be reached (20 to 100 fold more sensitive compared to current conventional method using STRs). After genotyping with KMRtype, the KMRtrack kit can be used for monitoring. Both KMRtype and KMRtrack kits are available as RUO and CE-marked IVD.

See specifications

Catalog

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82 Items

Product Status Reactions Catalog

KMRtrack® Starter Kit

Components

KMR004
KMR009
KMR010
KMR011
KMR013
KMR014
KMR016
KMR017
KMR019
KMR020
KMR028
KMR029
KMR030
KMR031
KMR033
KMR034
KMR035
KMR036
KMR037
KMR038
KMR039
KMR040
KMR041
KMR042
KMR043
KMR044
KMR045
KMR046
KMR047
KMR048
KMR049
KMR050
KMR051
KMR052
KMR053
KMR054
KMR055
KMR056
KMR057
Reference Gene 288
qPCR Buffer
Enzyme

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KMRtrack® Core Kit

Components

KMR009
KMR011
KMR013
KMR016
KMR019
KMR028
KMR030
KMR035
KMR036
KMR037
KMR038
KMR039
KMR040
KMR041
KMR042
KMR043
KMR044
KMR045
KMR046
KMR047
KMR048
KMR049
KMR050
KMR051
KMR052
KMR053
KMR054
KMR055
KMR056
KMR057

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KMRtrack® Extended Kit

Components

KMR004
KMR010
KMR014
KMR017
KMR020
KMR029
KMR031
KMR033
KMR034

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KMRtrack® Starter Kit

Components

KMR009
KMR011
KMR013
KMR016
KMR019
KMR028
KMR030
KMR035
KMR036
KMR037
KMR038
KMR039
KMR040
KMR041
KMR042
KMR043
KMR044
KMR045
KMR046
KMR047
KMR048
KMR049
KMR050
KMR051
KMR052
KMR053
KMR054
KMR055
KMR056
KMR057
Reference Gene 288
qPCR Buffer
Enzyme

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KMRtrack® KMR004

Components

KMR004

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KMRtrack® KMR004

Components

KMR004

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KMRtrack® KMR009

Components

KMR009

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KMRtrack® KMR009

Components

KMR009

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KMRtrack® KMR010

Components

KMR010

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KMRtrack® KMR010

Components

KMR010

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KMRtrack® KMR011

Components

KMR011

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KMRtrack® KMR011

Components

KMR011

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KMRtrack® KMR013

Components

KMR013

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KMRtrack® KMR013

Components

KMR013

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KMRtrack® KMR014

Components

KMR014

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KMRtrack® KMR014

Components

KMR014

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KMRtrack® KMR016

Components

KMR016

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KMRtrack® KMR016

Components

KMR016

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KMRtrack® KMR017

Components

KMR017

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KMRtrack® KMR017

Components

KMR017

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KMRtrack® KMR019

Components

KMR019

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KMRtrack® KMR019

Components

KMR019

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KMRtrack® KMR020

Components

KMR020

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KMRtrack® KMR020

Components

KMR020

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KMRtrack® KMR028

Components

KMR028

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KMRtrack® KMR028

Components

KMR028

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KMRtrack® KMR029

Components

KMR029

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KMRtrack® KMR029

Components

KMR029

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KMRtrack® KMR030

Components

KMR030

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KMRtrack® KMR030

Components

KMR030

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KMRtrack® KMR031

Components

KMR031

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KMRtrack® KMR031

Components

KMR031

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KMRtrack® KMR033

Components

KMR033

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KMRtrack® KMR033

Components

KMR033

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KMRtrack® KMR034

Components

KMR034

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KMRtrack® KMR034

Components

KMR034

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KMRtrack® KMR035

Components

KMR035

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KMRtrack® KMR035

Components

KMR035

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KMRtrack® KMR036

Components

KMR036

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KMRtrack® KMR036

Components

KMR036

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KMRtrack® KMR037

Components

KMR037

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KMRtrack® KMR037

Components

KMR037

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KMRtrack® KMR038

Components

KMR038

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KMRtrack® KMR038

Components

KMR038

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KMRtrack® KMR039

Components

KMR039

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KMRtrack® KMR039

Components

KMR039

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KMRtrack® KMR040

Components

KMR040

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KMRtrack® KMR040

Components

KMR040

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KMRtrack® KMR041

Components

KMR041

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KMRtrack® KMR041

Components

KMR041

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KMRtrack® KMR042

Components

KMR042

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KMRtrack® KMR042

Components

KMR042

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KMRtrack® KMR043

Components

KMR043

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KMRtrack® KMR043

Components

KMR043

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KMRtrack® KMR044

Components

KMR044

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KMRtrack® KMR044

Components

KMR044

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KMRtrack® KMR045

Components

KMR045

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KMRtrack® KMR045

Components

KMR045

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KMRtrack® KMR046

Components

KMR046

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KMRtrack® KMR046

Components

KMR046

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KMRtrack® KMR047

Components

KMR047

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KMRtrack® KMR047

Components

KMR047

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KMRtrack® KMR048

Components

KMR048

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KMRtrack® KMR048

Components

KMR048

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KMRtrack® KMR049

Components

KMR049

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KMRtrack® KMR049

Components

KMR049

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KMRtrack® KMR050

Components

KMR050

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KMRtrack® KMR050

Components

KMR050

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KMRtrack® KMR051

Components

KMR051

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KMRtrack® KMR051

Components

KMR051

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KMRtrack® KMR052

Components

KMR052

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KMRtrack® KMR052

Components

KMR052

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KMRtrack® KMR053

Components

KMR053

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KMRtrack® KMR053

Components

KMR053

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KMRtrack® KMR054

Components

KMR054

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KMRtrack® KMR054

Components

KMR054

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KMRtrack® KMR055

Components

KMR055

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KMRtrack® KMR055

Components

KMR055

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KMRtrack® KMR056

Components

KMR056

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KMRtrack® KMR056

Components

KMR056

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KMRtrack® KMR057

Components

KMR057

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KMRtrack® KMR057

Components

KMR057

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Specifications

The GenDx Chimerism Monitoring workflow

 

Advantages of KMRtype & KMRtrack

  • Use of 39 markers strategically placed over 17 chromosomes: This way, the chance of finding an informative marker is increased.

Chromosomal location of KMRtype & KMRtrack markers

  • Multiple donor analysis: With our highly sensitive system multiple donors can be traced simultaneously. With the increased use of double cord blood donations this feature improves the opportunities for highly sensitive and longitudinal monitoring.

 

  • Up to 8 samples per genotyping experiment: With a multiplexed assay the number of reactions and reagents needed per sample is minimized, enabling an experimental set-up of up to 8 samples per run (when applying a 96-well plate and the KMRtype Core kit). Samples from both recipient and donor can be analyzed in separate experiments, providing additional flexibility.

 

  • Compatible with most common qPCR machines: ABI (ViiA7 v1.2.4 / 7500 Fast v2.0.6 / 7500 v1.3.1/1.4/2.0.2/2.0.6/2.3), QuantStudio (5 v1.2 / 6 v1.2, v1.3 / 7 v1.2 / 12K v1.2 / DX v1.2), BioRad (CFX 96 v1.6/3.0/3.1).

 

 

Kit content RUO version

The Core and Extended kits for KMRtype and KMRtrack differ in number of assays that they contain. The Core kit offers 30 assays, while an additional 9 assays can be found in the Extended kit, which can be applied in cases where no informative marker was obtained with the Core kit. You can apply both the Core and Extended kit at the same time, genotyping your samples for 39 assays in one go. There are also kits available that include reference assay, buffer and enzyme. More info about the kit content can be found in instructions for use.

 

Kit content IVD version

The Core and Extended kits for KMRtype and KMRtrack contain all 39 assays, reference assay, buffer, and enzyme.

 

To be supplied by the user:

  • Pipettes and tips (hydrophobic filters)
  • Ice or cooling block
  • Optical 96-wells reactions plates
  • Eppendorf tubes
  • PCR tubes, strips or plates
  • Optical adhesive seals
  • Micro centrifuge
  • Microtiter Plate Centrifuge
  • Vortex
  • MilliQ water
  • Compatible qPCR machine

Downloads

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