Generally, deceased donor typing is carried out using intermediate-resolution HLA-typing methodologies. Achieving high-resolution typing across HLA-loci before transplantation could significantly improve donor organ allocation and virtual crossmatching, as it aligns resolution between HLA antibody definition and HLA typing. Offering benefits particularly for highly-sensitised recipients.
In this webinar, Lizzy Russell-Lowe, Clinical Scientist at Manchester Royal Infirmary, will present a study in which HLA typing results obtained with the GenDx NGS-Turbo® kit, using Oxford Nanopore Technologies sequencing, were retrospectively compared with standard intermediate-resolution HLA typing methods. The NGS-Turbo® kit produced concordant typing results for all samples in less than 4 hours.
The webinar will explore the clinical utility of having high-resolution typing available in a deceased-donor setting, and the feasibility of achieving this in a timely manner.
