๐ฅ๐ฒ๐ด๐ถ๐๐๐ฒ๐ฟ ๐ณ๐ผ๐ฟ ๐ผ๐๐ฟ ๐ป๐ฒ๐ ๐๐ฒ๐ฏ๐ถ๐ป๐ฎ๐ฟ!
Our Scientist Cynthia Kramer, PhD, will provide an overview of the current HLA molecular matching approaches as well as ongoing discussion in the field.
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February 25
๐ 12:00 CET๏ธฑ19:00 CET
๐Online
๐๐ฏ๐ผ๐๐ ๐๐ฒ๐ฏ๐ถ๐ป๐ฎ๐ฟ
Within the field of solid organ transplantation, HLA molecular matching is a hot topic. Over the past decade, multiple approaches have been introduced to predict HLA immunogenicity on the molecular level.
While, indeed, at the population level, an increasing number of molecular mismatches is strongly associated with the formation of de novo donor-specific antibody and worse graft survival after transplantation, at the patient level, it is not necessarily a numbers game. Not every HLA molecular mismatch is equally immunogenic, and immunological risk assessments require more than counting mismatches.
