SBTengine® Software

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What is SBTengine?

SBTengine is a dedicated typing software package for the high-resolution identification of HLA alleles by Sanger sequencing-based typing (SBT).

The software is intended for in vitro diagnostic use by professional users in diagnostic laboratories, such as laboratory technicians and physicians, trained in HLA-typing and DNA sequencing.

SBTengine supports fast and accurate analysis of HLA class I (A, B and C) and class II (DR, DP and DQ) loci, but can also be utilized for other polymorphic gene systems including minor histocompatibility antigens: DLA, KIR, MICA, MICB, CAJA, MAFA, MAMU and PATR.


Is SBTengine CE-IVD marked?

Yes, SBTengine is marked as CE-IVD
SBTengine® is only available as IVD in Europe (CE) and the USA (FDA).


What are the system requirements of SBTengine?

Minimum system requirements:

  • Windows Vista, Windows 7*
  • 2 GB RAM
  • 80 MB free disk space
  • Network connection allowing TCP/IP traffic to and from port 3500
  • Microsoft .NET framework 2.0


Recommended system requirements:

  • Windows 10
  • 2 GB RAM
  • Internet connection for license validation and automatic updates
  • 250 MB free disk space
  • Microsoft .NET framework 2.0


Can I install the software on a Mac OS rather than on a PC?

We do not support the use of SBTengine on a Mac OS. However, it may be possible to run the software on a Mac OS if you are using a Windows virtual machine.

What kind of SBTengine licenses do you offer?

We offer standard and premium versions of SBTengine. The standard version includes 1 year of updates and support. The premium version includes 5 years of updates and support. After these periods, additional update packages can be purchased.

How often is SBTengine updated?

SBT-engine is updated every 3-6 months. Every update includes the latest IMGT database, updated allele frequency tables, and new software features.

What is the latest version of SBTengine?

The latest version is 3.24.0

IMGT/HLA release 3.37.0

You can check your version by clicking <Help> and <About>

You can see what's new in this version by clicking <New features>


How can I install SBTengine updates on my computer?

You can download updates from our website here.

Click "SBTengine Software Download". Then, click on the download link (.msi file).


Is there a manual of the SBTengine software?

The SBTengine Instructions for Use (IFU) can be downloaded here. The IFU gives a brief introduction of the SBTengine workflow, from importing data to generating a typing report.

There is also an extensive Help section in SBTengine itself, which can be found on the Glossary tab. The Help section can also be accessed online here.

You can also request an online software demo or join our teaching session at EFI or ASHI for an advanced course in HLA typing with SBTengine.


Can I request a free trial of SBTengine?

Yes you can! Fill out the request form here.


end faq


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